DNase VII of human placenta. Mechanism studies.
نویسندگان
چکیده
منابع مشابه
Immunohistological and Elution Studies of the Human Placenta
An immunohistological survey of 28 full-term human placentas has demonstrated deposits of IgG, beta1C, beta1E, and fibrinogen/fibrin in areas of fibrinoid necrosis and on the trophoblast basement membrane in approximately 35% of placental villi. Traces of IgM were detected at similar sites in 18 of 28 full-term placentas. In 11 specimens of immature placentas (10-18 wk gestation) traces of IgG ...
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In the previous papers (Ito and Higashi, 1961; Higashi, 1961), it was reported that a protein which stimulates the increase of the number and size of the fatty granules in the crop milk of pigeons was obtained from human placenta by the fractional precipitation with ammonium sulfate. The present communication describes the procedure of purification of this biologically active substance and some...
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Mucopolysaccharidosis VII (MPS VII) is a lysosomal storage disease in which deficiency in beta-glucuronidase results in glycosaminoglycan (GAG) accumulation in and around cells, causing shortened long bones through mechanisms that remain largely unclear. We demonstrate here that MPS VII mice accumulate massive amounts of the GAG chondroitin-4-sulfate (C4S) in their growth plates, the cartilagin...
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The placenta is a key organ for pregnancy evolution and fetal growth. Placental anatomic abnormalities may affect the placental functions, interfering in turn with maternal and or fetal wellbeing. This chapter describes the placental development, the macroscopic aspect and the histological characteristics through the gestation. The aim of this chapter is to provide updated information to help c...
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Coagulation factors belong to a family of plasma glycosylated proteins that should be activated for appropriate blood coagulation. Congenital deficiencies of these factors cause inheritable hemorrhagic diseases. Factor VII (FVII) deficiency is a rare bleeding disorder with variable clinical symptoms. Various mutations have been identified throughout the F7 gene and can affect all the protein do...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1985
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)89181-5